Wednesday, August 28, 2019
How Brian Imaging Could Help Predict Alzheimers Essay
How Brian Imaging Could Help Predict Alzheimers - Essay Example To date there is a lack of reliable drug that can be used to decelerate the progress of Alzheimerââ¬â¢s disease. Although many drugs have been tested scientists and drug manufacturers blame the timing when these drugs have been administered to patients of the disease. They claim that many of the drugs are administered at a time when the progress of the disease makes it difficult for any significant improvement to take place. The pharmaceutical company Eli Lilly developed gamma secretase inhibitor but this drug didnââ¬â¢t prove successful. Sangram Sisodia, director of the Center for Molecular Neurobiology at the University of Chicago explained that the drug was tested on the wrong group of patients. New studies, however, have shown that there is hope for Alzheimerââ¬â¢s patients. Recent presentations at the Society for Neuroscience conference recently held in San Diego showed that brain imaging may help in the prediction of the disease. Researchers believed that changes in the brain will help to qualify patients to undergo clinical tests of new drugs. They are also hopeful that brain imaging will help in the selection of persons for clinical testing before dementia is developed. Reliable drugs testing can become possible if persons found with mild cognitive impairment are used for clinical testing as indicated by recent researches. Not everyone who has this condition will develop Alzheimerââ¬â¢s as revealed by a graduate student of Rush University Medical Center in Chicago. The study highlighted the substantia innominata section of the brain. Of the 47 persons who had mild cognitive impairment, 22 developed Alzheimerââ¬â¢s over a six year period. They were found to have significant thinning in three connected areas of the cortex involved in memory, attention, and integration of sensor and motor integration. A second study revealed that the caudate nucleus section of the brain shrunk significantly in elderly persons diagnosed with
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